The Vu Gia-u Bon River Basin is in central Vietnam and covers an area of more than 10,000 km², including some important tourist destinations. Plastic pollution is a major problem in the basin and the issue has in recent time become an important element of the political agenda, on national as well as local levels.This makes Vu Gia-u Bon River Basin well suited for applying the Source-To-Sea Framework for Marine Litter Prevention. The film describes the approach, its outcome, and discusses potential challenges and how to address them.The film describes the source-to-sea pilot project in Vu Gia-Thu Bon River Basin in Vietnam. It provides insights on how the source-to-sea approach can be applied, how it can benefit stakeholders at all levels, and what the potential challenges are.